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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHAF1B All Species: 26.67
Human Site: S214 Identified Species: 39.11
UniProt: Q13112 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13112 NP_005432.1 559 61493 S214 F N V S K M L S G I G A E G E
Chimpanzee Pan troglodytes XP_525468 559 61460 S214 F N V S K M L S G I G A E G E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544875 668 72082 S332 F N V S K M L S G V G A E G E
Cat Felis silvestris
Mouse Mus musculus Q9D0N7 572 63114 S214 F N I S K M L S G Q G P E G E
Rat Rattus norvegicus NP_001019912 572 62715 S214 F N V S K M L S G Q G P E G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512498 575 62833 S214 F N V T K M L S G T G A E G E
Chicken Gallus gallus Q5R1S9 566 62559 S214 F N V T K M P S E S G A E G E
Frog Xenopus laevis Q8QFR2 1013 112021 D217 T S I T K P F D E C G G T T H
Zebra Danio Brachydanio rerio NP_998177 236 26626
Tiger Blowfish Takifugu rubipres O42611 1025 111838 S217 A N I T K P F S E C G G T T H
Fruit Fly Dros. melanogaster NP_610589 747 83376 L218 H R V S K C V L P V K E D H E
Honey Bee Apis mellifera XP_624307 452 51453 E117 S E E T K D K E Q W I S W K V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001191151 639 69080 L210 H H V N K L T L A A A G N N G
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132835 506 55177 A171 D P L G Q Y I A S L S S D R T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974991 487 54088 A152 S V H Q I L D A H C H Y V Q G
Baker's Yeast Sacchar. cerevisiae Q04199 468 51234 W133 N K E K W V V W K R L R G G S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 73.8 N.A. 82.3 82.6 N.A. 75.6 72.7 20.9 33.6 20.6 35.7 38.6 N.A. 44.1
Protein Similarity: 100 99.8 N.A. 76.3 N.A. 88.4 88.4 N.A. 82 81.4 33 38.4 31.7 49.6 56.1 N.A. 58.2
P-Site Identity: 100 100 N.A. 93.3 N.A. 80 86.6 N.A. 86.6 73.3 13.3 0 26.6 26.6 6.6 N.A. 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 86.6 N.A. 93.3 80 33.3 0 40 46.6 20 N.A. 33.3
Percent
Protein Identity: N.A. 37.2 N.A. 35.6 25.7 N.A.
Protein Similarity: N.A. 53.1 N.A. 54.3 42.9 N.A.
P-Site Identity: N.A. 0 N.A. 0 6.6 N.A.
P-Site Similarity: N.A. 46.6 N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 0 0 13 7 7 7 32 0 0 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 19 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 7 7 7 0 0 0 0 13 0 0 % D
% Glu: 0 7 13 0 0 0 0 7 19 0 0 7 44 0 50 % E
% Phe: 44 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 0 0 38 0 57 19 7 50 13 % G
% His: 13 7 7 0 0 0 0 0 7 0 7 0 0 7 13 % H
% Ile: 0 0 19 0 7 0 7 0 0 13 7 0 0 0 0 % I
% Lys: 0 7 0 7 75 0 7 0 7 0 7 0 0 7 0 % K
% Leu: 0 0 7 0 0 13 38 13 0 7 7 0 0 0 0 % L
% Met: 0 0 0 0 0 44 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 50 0 7 0 0 0 0 0 0 0 0 7 7 0 % N
% Pro: 0 7 0 0 0 13 7 0 7 0 0 13 0 0 0 % P
% Gln: 0 0 0 7 7 0 0 0 7 13 0 0 0 7 0 % Q
% Arg: 0 7 0 0 0 0 0 0 0 7 0 7 0 7 0 % R
% Ser: 13 7 0 38 0 0 0 50 7 7 7 13 0 0 7 % S
% Thr: 7 0 0 32 0 0 7 0 0 7 0 0 13 13 7 % T
% Val: 0 7 50 0 0 7 13 0 0 13 0 0 7 0 7 % V
% Trp: 0 0 0 0 7 0 0 7 0 7 0 0 7 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _